Family history can play a part in developing Alzheimer’s. In recent times, a new form of diabetes has become part of the discussion, which is known as Diabetes Type 3,” said Dr Anurag Bansal, technical head N&E and Director – Lab Operations (Gurugram Reference Lab), SRL Diagnostics.
Type 1, Type 2, GDM (Gestational Diabetes Mellitus), MODY (Maturity Onset Diabetes of the Young) and LADA (Latent Autoimmune Diabetes of Adulthood). “We all are aware about five types of diabetes i.e. Type 3 diabetes is a proposed term for Alzheimer’s disease resulting from insulin resistance (which is the primary problem associated with T2DM) and insulin deficiency (which is the primary problem in type 1 diabetes), said Dr Anupama Singh, senior consultant, Vimhans Nayati Super Specialty Hospital, New Delhi, while pointing out how “a limited number of published reviews have suggested mechanisms linking AD with insulin resistance”.ĭoctors that spoke to said that while what causes Alzheimer’s disease or exactly how AD and T2DM are connected is not yet known, they point out that “high blood sugar can harm the brain in several ways”. According to various other studies, it is being considered that T2DM is a risk factor for future development of AD, the most prominent cause of cognitive failure in the elderly. In a study cohort from Manhattan in 1992–1994 and then in 1999–2001 Cheng et al., it was demonstrated that T2DM is associated strongly with late-onset AD after adjustment of sex and age, as per National Center for Biotechnology Information.
Epidemiological studies show that T2DM increases the risk of AD by at least two-fold as per researchers Barbagallo and Dominguez in 2014.
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